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PEOPLE

Dr. Giacomo Giacomelli

Postdoctoral Researcher

 

Research topics & projects

Corynebacterium glutamicum, SOS response, SMLM, DivIVA

Education & positions

since 2021    Postdoctoral researcher, CAU Kiel, Germany

2019 - 2021  PhD Student (continuation), Christian-Albrechts-Universität zu                         Kiel (CAU) (affiliated to the Graduate Program Life Science                                 Munich) in Germany

2014 - 2019  PhD Student, LMU (affiliated to the Graduate Program Life                               Science Munich) in Germany

2012 - 2014  Master of Science (M.Sc.) in Biology, Ludwig-Maximilians-                                   Universtät München (LMU), Germany  

2009 - 2012  Bachelor of Science (Biomolecular science and technology),

                       Universitá degli studi di Trento, Italy

Publications

Pöhl S, Giacomelli G, Meyer FM, Kleeberg V, Cohen EJ, Biboy J, Rosum J, Glatter T, Vollmer W, van Teeseling MCF, Heider J, Bramkamp M, Thanbichler M. Nat Commun. 2024 Sep 2;15(1):7616.

https://doi.org/10.1038/s41467-024-51790-z

Weiß M, Giacomelli G, Assaya MB, Grundt F, Haouz A, Peng F, Petrella S, Wehenkel AM, Bramkamp M. The MksG nuclease is the executing part of the bacterial plasmid defense system MksBEFG. Nucleic Acids Res. 2023 Mar 7:gkad130. https://doi.org/10.1093/nar/gkad130 

Hołówka J, Łebkowski T, Feddersen H, Giacomelli G, Drużka K, Makowski Ł, Trojanowski D, Broda N, Bramkamp M, Zakrzewska-Czerwińska J. 2023. Mycobacterial IHF is a highly dynamic nucleoid-associated protein that assists HupB in organizing chromatin. Frontiers in Microbiology 14.

https://doi.org/10.3389/fmicb.2023.1146406

Giacomelli G, Feddersen H, Bramkamp M. Overcoming the signal overlap in super-resolution microscopy - A beginner's guide to single-molecule localization microscopy colocalization. Wiley Analytical Science. 2022 Nov 9.

https://analyticalscience.wiley.com/do/10.1002/was.0004000306/

Bachmaier S, Giacomelli G, Calvo-Alvarez E, Vieira LR, Van Den Abbeele J, Aristodemou A, Lorentzen E, Gould MK, Brennand A, Dupuy JW, Forné I, Imhof A, Bramkamp M, Salmon D, Rotureau B, Boshart M. A multi-adenylate cyclase regulator at the flagellar tip controls African trypanosome transmission. Nat Commun. 2022 Sep 16;13(1):5445.

https://doi.org/10.1038/s41467-022-33108-z

Giacomelli G*, Feddersen H*, Peng F, Martins GB, Grafemeyer M, Meyer F, Mayer B, Graumann PL, Bramkamp M. Subcellular Dynamics of a Conserved Bacterial Polar Scaffold Protein. Genes (Basel). 2022 Jan 30;13(2):278. https://doi.org/10.3390/genes13020278

Babl L, Giacomelli G, Ramm B, Gelmroth AK, Bramkamp M, Schwille P. CTP-controlled liquid-liquid phase separation of ParB. J Mol Biol. 2022 Jan 30;434(2):167401. https://doi.org/10.1016/j.jmb.2021.167401

Osorio-Valeriano M, Altegoer F, Das CK, Steinchen W, Panis G, Connolley L, Giacomelli G, Feddersen H, Corrales-Guerrero L, Giammarinaro PI, Hanßmann J, Bramkamp M, Viollier PH, Murray S, Schäfer LV, Bange G, Thanbichler M. The CTPase activity of ParB determines the size and dynamics of prokaryotic DNA partition complexes. Mol Cell. 2021 Oct 7;81(19):3992-4007.e10. ​https://doi.org/10.1016/j.molcel.2021.09.004

Kołodziej M, Trojanowski D, Bury K, Hołówka J, Paściak M, Matysik W, Kąkolewska H, Feddersen H, Giacomelli G, Bramkamp M, Konieczny I, Zakrzewska-Czerwińska J. Lsr2, a nucleoid-associated protein influencing mycobacterial cell cycle. Sci Rep 11, 2910 (2021). 
https://doi.org/10.1038/s41598-021-82295-0

Böhm K, Giacomelli G, Meyer F, Bramkamp M. Chromosome Organization and Cell Growth of Corynebacterium glutamicum. In: Inui M., Toyoda K. (eds) Corynebacterium glutamicum. Microbiology Monographs, vol 23. 2020,  Springer, Cham.
https://doi.org/10.1007/978-3-030-39267-3_1.

Böhm K, Giacomelli G, Schmidt A, Imhof A, Koszul R, Marbouty M, Bramkamp M. Chromosome organization by a conserved condensin-ParB system in the actinobacterium Corynebacterium glutamicum. Nat Commun. 2020 Mar 20;11(1):1485.
https://doi.org/10.1038/s41467-020-15238-4

Toro-Nahuelpan M, Giacomelli G, Raschdorf O, Borg S, Plitzko JM, Bramkamp M, Schüler D, Müller FD. MamY is a membrane-bound protein that aligns magnetosomes and the motility axis of helical magnetotactic bacteria. Nat Microbiol. 2019 Nov;4(11):1978-1989.
https://doi.org/10.1038/s41564-019-0512-8. Epub 2019 Jul 29.

Bracher S, Hilger D, Guérin K, Polyhach Y, Jeschke G, Krafczyk R, Giacomelli G, Jung H. Comparison of the functional properties of trimeric and monomeric CaiT of Escherichia coli. Sci Rep. 2019 Mar 7;9(1):3787.
https://doi.org/10.1038/s41598-019-40516-7.

Martins GB, Giacomelli G, Goldbeck O, Seibold GM, Bramkamp M. Substrate-dependent cluster density dynamics of Corynebacterium glutamicum phosphotransferase system permeases. Mol Microbiol. 2019 May;111(5):1335-1354.
https://doi.org/10.1111/mmi.14224. Epub 2019 Mar 18.

Bach JN, Giacomelli G, Bramkamp M. Sample Preparation and Choice of Fluorophores for Single and Dual Color Photo-Activated Localization Microscopy (PALM) with Bacterial Cells. Methods Mol Biol. 2017;1563:129-141.
https://doi.org/10.1007/978-1-4939-6810-7_9.

Schubert K, Sieger B, Meyer F, Giacomelli G, Böhm K, Rieblinger A, Lindenthal L, Sachs N, Wanner G, Bramkamp M. The Antituberculosis Drug Ethambutol Selectively Blocks Apical Growth in CMN Group Bacteria. mBio. 2017 Feb 7;8(1):e02213-16.
https://doi.org/10.1128/mBio.02213-16.

Giacomo.JPG
Dr. Giacomo Giacomelli
Postdoctoral Researcher

ggiacomelli@ifam.uni-kiel.de

+49 (0)431 880 5348

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